Control of cell migration during Caenorhabditis elegans development.
نویسندگان
چکیده
In Caenorhabditis elegans, cell migration is guided by localized cues, including molecules such as EGL-17/FGF and UNC-6/netrin. These external cues are linked to an intracellular response to migrate, at least in part, by CED-5, a homolog of DOCK180/MBC, and MIG-2, a Rac-like GTPase. In addition, metalloproteases are required for a cell migration that controls organ shape.
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عنوان ژورنال:
- Current opinion in cell biology
دوره 11 5 شماره
صفحات -
تاریخ انتشار 1999